SnapShot: Formation of mRNPs

SnapShot: Formation of mRNPs

Multiple adaptor proteins (e.g., Yra1/Aly/REF1 and SR proteins) drive mRNP • export by loading dimeric export receptor (Mex67-Mtr2/TAP-p15/NXF1-NXT1). In yeast, TREX complex recruited to polymerase; DECD helicase Sub2 loads • Yra1 onto mRNA. In vertebrates, TREX binds cap via splicing-dependent interaction of Aly/REF1(vertebrate Yra1) with CBP80. Export coupled to transcription via SAGA chromat...

HypothesisEukaryotic mRNPs

Although highly efficient, the clear disadvantage of the prokaryotic operon is the constraint placed upon gene expression by physically coupling the production of multiple proteins in a fixed group. For example, the presence of a nonsense mutation in an operon can result Durham, North Carolina 27710 in polarity effects that disrupt downstream functions. Also, the ability to independently regula...

‏‎suppression of coke formation in thermal cracking by coke inhibitors‎‏

‏‎the main purpose of this research was to:1.develop a coking model for thermal cracking of naphtha.2.study coke inhibition methods using different coke inhibitors.developing a coking model in naphtha cracking reactors requires a suitable model of the thermal cracking reactor based on a reliable kinetic model.to obtain reliable results all these models shall be solved simultaneously.for this pu...

formation and evolution of regional organizations: the case study of the economic cooperation organization (eco)

abstract because of the many geopolitical, geo economical and geo strategically potentials and communicational capabilities of eco region, members can expand the convergence and the integration in base of this organization that have important impact on members development and expanding peace in international and regional level. based on quality analyzing of library findings and experts interv...

HypothesisEukaryotic mRNPs May Represent Posttranscriptional Operons